The biggest signs that the love is gone in a marriage is when a spouse or even both have absolutely given up, when they have lost hope. It is all shown by their behavior. They have stopped caring, they have stopped fighting, they have stopped talking. They have stopped it all. They have run out of energy. They are defeated. Tired. Completely powerless.
This is one of the hardest things in life to accept. The moment you realize that the love is gone from your relationship. Sometimes the love can be revived, sometimes it's possible to bring it back; and many times when the heart has been completely shattered, there is nothing that can be done.
Almost everyone of us has seen it happening to a couple we know. They no longer are affectionate, they no longer kiss, no longer hold hands, no longer share the same bed, no longer talk to each other, they no longer care.